Stock UICP vs. after market hard pipe

So I've been wondering and searching, we all know the stock UICP expands during increased boost levels, but how much will it make a difference for daily drivers that don't mess around with the boost level of the car? It seems that most people on this forum speak in terms of a heavy modding mind set. I know the more boost you run, the more the squishy pipe is going to expand. But what if you're not messing with the boost levels (with a boost controller)? Will the drop in throttle response be that much?

How much difference is it going to make for a conservatively tuned car with just a panel filter, cat back, fmic, and hi flow cat?